Gastroenterologist Vivek Kaul, MD, reviews his top picks for primary care clinicians from DDW2022 including papers on the esophagus and the colon and then finishing up with the liver.
Hi. I'm Dr Vivek Kaul and I'm professor of medicine in the Division of Gastroenterology & Hepatology at the University of Rochester Medical Center. It gives me great pleasure to do this presentation in collaboration with Medscape. I have just returned from Digestive Disease Week 2022, which is the largest international GI conference, and it was held in person for the first time in 3 years due to the pandemic.
My collection of papers is divided into the esophagus and the colon, and then finishing up with the liver.The first paper in the esophagus realm is a multicenter study called"The Association of Proton Pump Inhibitor Use and Cognitive Decline and Incident Dementia in Older Adults." The researchers looked at about 19,000 patients, 65 years and older, who were on PPI therapy and had no significant disability or prior dementia.
The second paper,"Double-Blind Randomized Trial of the Potassium-Competitive Acid Blocker Vonoprazan vs. the Proton Pump Inhibitorin U.S. and European Patients with Erosive Esophagitis," is also related to GERD [gastroesophageal reflux disease] therapy but introduces a new paradigm known as potassium-competitive channel blockers. This is a new drug that has now become available, called vonoprazan.
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