A new drug could solve the problem of cataracts, without surgery

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A new drug could solve the problem of cataracts, without surgery
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Moving away from surgery is the only remedy.

Conventionally, surgery has been the only remedy for this condition. Still, a team of researchers led by

Professor Barbara Pierscionek at ARU has carried out advanced tests of an oxysterol compound as an anti-cataract drug. An oxysterol is a derivative of cholesterol that plays a role in many cellular functions, including autophagy - conserved cell degradation to remove unnecessary components. The compound called VP1-001, when used in laboratory-based trials, showed a marked improvement in the refractive index profile for 61 percent of the cases. In comparison, the press release said that lens opacity was found to have been decreased in 46 percent of the cases. Ais a crucial parameter in determining the focusing capacity of the eye. The drug is therefore acting to restore the protein organization inside the lens.

"It is the first research of this kind in the world," said Professor Pierscionek in the press release."The positive effects of the compound have been proposed as an anti-cataract drug but never before tested on the optics of the lens. It is a significant step forward towards treating this extremely common condition with drugs rather than surgery."However, the studies also showed improvements in only some types of cataracts and not all.

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