A risk score developed using biological, psychological, and social factor data from the uk_biobank can predict different pain conditions and the prognosis of chronic pain up to 9-years later evp82 TanguaySabourin
Additional assessments in a subset of participants recruited at baseline were conducted by the UKB using online questionnaires. Experience of pain questionnaires were administered about 8–13 years after the baseline visit to allow better phenotyping of individuals with chronic pain. A subset of 332,587 participants were sent invitations and 167,255 filled out the online questionnaire.
Of the participants from the online UKB, only those reporting chronic pain were included in this study. Participants reporting PAO were not exposed to a subset of the questionnaire and were therefore excluded from the related analyses. Similarly, participants missing data at any of the pain sites examined were excluded .Participants were asked whether they experienced pain that interfered with their usual activities at any major anatomical sites in the last month.
. Variables were organized through an iterative approach along a hierarchical framework from 99 variables into ten categories forming three distinct domains . The three domains are as follows:The mental health domain includes three categories neuroticism based on 12 neurotic behaviors closely linked to negative effect; traumas including six events; and mood .
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