A vaccine targeting resistant tumours by dual T cell plus NK cell attack - Nature

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A vaccine targeting resistant tumours by dual T cell plus NK cell attack - Nature
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A Nature research paper presents a new type of cancer vaccine that can thwart the defensive response of tumours to vaccine-induced immune attack

K.W.W. serves on the scientific advisory board of TCR2 Therapeutics, TScan Therapeutics, SQZ Biotech and Nextechinvest, and he receives sponsored research funding from Novartis. He is a co-founder of Immunitas Therapeutics, a biotech company.thanks Wolfgang Wick and the other, anonymous, reviewer for their contribution to the peer review of this work.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Extended Data Fig.

, Quantitative RT-PCR analysis of luciferase and MICB mRNA in the prostate of WT and MICB-tg mice normalized to mouse, Quantification of day 14 MICB-specific serum Ab titers in WT and MICB-tg mice immunized with Ctrl-vax or MICB-vax without MSR or with MSR scaffold., Quantification of MICB-specific serum Ab titers in mice immunized with Ctrl-vax or MICB-vax using differing protein doses, 50μg , 100μg or 200μg .

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