Immune cells in brain and spinal fluid become dysregulated and ‘a little angry’ as we age. Cerebrospinal fluid immune system is drastically altered in individuals with cognitive impairment Discovery could potentially be used to treat inflammation of the brain First thorough analysis of i
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Gate’s team of scientists observed genetic changes in the CSF immune cells in older healthy individuals that made the cells appear more activated and inflamed with advanced age. “It could be the degenerating brain activates these cells and causes them to clone themselves and flow to the brain,” Gate said. “They do not belong there, and we are trying to understand whether they contribute to damage in the brain.”
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