Experts have their eyes on a particular adenovirus, type 41, as a potential cause. It has been identified in a majority of cases in Europe and many in the U.S.
In general, there can be hundreds of potential causes of hepatitis: Liver inflammation can result from toxins, viruses or contaminated food and water.
Dr. Markus Buchfellner, a pediatric infectious diseases fellow at the University of Alabama at Birmingham, was the first to notice the unusual pattern of unexplained hepatitis in kids in the U.S. and report it to the CDC. He and other experts have wondered whether pandemic lockdowns resulted in reduced exposure to adenoviruses in general, perhaps making young kids more vulnerable to them.
Still, the WHO is also looking at whether a prior Covid infection — even a mild or asymptomatic case — could have somehow prompted kids’ immune systems to react abnormally to otherwise harmless adenoviruses.
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