Bipolar Disorder is Associated with Premature Mortality

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Bipolar Disorder is Associated with Premature Mortality
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The risk of premature death is doubled in persons with bipolar disorder.

People with bipolar disorder are 7 times more likely to die from unnatural causes than the general population.It is estimated that about one percent of the population suffers from bipolar disorder, and the illness is associated with disruption of relationships, employment, and everyday functioning. In addition, bipolar disorder has been increasingly associated with premature death.

Biazus and colleagues conducted a systematic review and meta-analysis of previously published research regarding mortality in people with bipolar disorder as compared to appropriate control populations. By using specific quality criteria, they combined data from 57 unique studies involving 678,353 persons with bipolar disorder. Individuals in these studies came from 16 different countries, mostly in Western Europe, the United States, and Asia.

The Biazus team conducted additional analyses to investigate specific causes of death. They found that the relative risk of death fromand other unnatural causes is markedly increased. The relative risk from suicide is about 11.6, whereas the relative risk of dying from unnatural causes is about 7.3.Bipolar disorder can be psychologically devastating, leading persons to take their own lives or act in ways that increase the risks of death from unnatural causes.

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