Change Makers: David Ricks Is Leading With Purpose

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What if we could prevent, cure, or even reverse diseases like Alzheimer's, cancer and diabetes? That's what ChangeMakers is all about. via drjohnwhyte

—30 years ago, life expectancy was quite short. Today they're not quite chronic diseases; you can die of other things. But getting close, we're seeing survival in people who have early intervention with adjuvant surgery and then treatment with hormone therapy. We have a new medicine that adds to that, in various stages of metastatic treatment. People can live a very long time — decades — with a cancer diagnosis now.

Can we get better using cells, using laboratory techniques, to look for protein markers in the blood? They all have reduced risk, but not enough. Through two types of innovation — the molecule we're testing and the way we test — we are going to get closer to proof. Next year will be exciting; we have our phase 3 readout. But the molecule itself we've been treating with anti-amyloid antibodies and other drugs for a while and just missing. Probably one of the reasons for that is they don't work deep enough; they don't get rid of enough amyloid and they don't do it fast enough.

And so there's tremendous bias in those systems for advanced care, and that needs the most work. We're committed to doing that. We have this-targeted drug that I mentioned before, which requires a genome sample. We're subsidizing tremendously that process so it's available to more Americans.

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