China approves world-first inhaled COVID-19 vaccine

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China approves world-first inhaled COVID-19 vaccine
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The needle-free vaccine is the first of over 100 oral or nasal vaccines currently in development around the world

China has approved the world’s first inhaled COVID-19 vaccine, the vaccine maker CanSino Biologics in Tianjin, China has announced.

The needle-free vaccine is the first approved of over 100 oral or nasal vaccines currently in development around the world, according to a World Health Organization database. Scientists hope that administering vaccines through the nose or mouth could prepare the immune cells of the thin mucous membranes there, preventing the spread of even mild cases of the illness by killing the virus as it enters the body.

Another clinical trial, published Jul. 26 in The Lancet, showed the immunity levels produced by two inhalations of the vaccine 28 days apart reached the same as those produced by one intramuscular shot. For instance, in a recent study of the Convidecia Air vaccine published on a preprint server without peer review, two Sinovac shots followed by a lower dose inhaled vaccine produced detecable levels of omicron neutralizing antibodies in 92.5% of cases, whereas a higher dose generated detectable antibodies in 88.9% of cases. The number for both groups, however, dropped to around 70% six months later.

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