Genetically editing poplar trees reduces the resources required to harvest their wood's cellulose, which makes up paper
Wang, Barrangou and their colleagues wondered if they could genetically edit poplar trees, which are widely used to make paper, to have a lower concentration of lignin while maintaining their structure.
To do this, they used machine learning to analyse the genome of the poplar tree and highlight combinations of genes they could edit usingThe researchers analysed this data to determine which combinations had the best chance of reducing a tree’s lignin content while ensuring it remained strong, finding that just 0.5 per
cent of these editing methods fit the bill. They chose seven that they deemed to be particularly robust, from which they grew 174 different variants of CRISPR-edited poplar trees.
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