Decoding a direct dialog between the gut microbiota and the brain
Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions. Scientists from the Institut Pasteur , Inserm and the CNRS have discovered that hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly.
Using brain imaging techniques, the scientists initially observed that the NOD2 receptor in mice is expressed by neurons in different regions of the brain, and in particular, in a region known as the hypothalamus. They subsequently discovered that these neurons' electrical activity is suppressed when they come into contact with bacterial muropeptides from the gut."Muropeptides in the gut, blood and brain are considered to be markers of bacterial proliferation," explains Ivo G.
The neurons thus appear to detect bacterial activity as a direct gauge of the impact of food intake on the intestinal ecosystem."
Norge Siste Nytt, Norge Overskrifter
Similar News:Du kan også lese nyheter som ligner på denne som vi har samlet inn fra andre nyhetskilder.
Scientists resurrect ancient enzymes to improve photosynthesis -- ScienceDailyA new study describes a breakthrough in the quest to improve photosynthesis in certain crops, a step toward adapting plants to rapid climate changes and increasing yields to feed a projected 9 billion people by 2050.
Les mer »
Scientists identify potential new 'soldier' for cancer immunotherapy -- ScienceDailyThe new cells, which the scientists have dubbed killer innate-like T cells, differ in several notable ways from the conventional target of many immunotherapies.
Les mer »
Decoding the Past – Scientists Uncover the Origin of Mysterious Giant Extinct Marine Reptile GraveyardFor many years, researchers have been studying a state park in Nevada, but despite their efforts, the reason for the high number of ichthyosaur deaths in the area some 230 million years ago remains a mystery. Blue and humpback whales, along with other marine giants of today, regularly undertake l
Les mer »
How scientists are decoding what the past smelled like | CNNSmell has been unfairly ignored in attempts to understand the past, say researchers, who are using new techniques to reconstruct ancient scents and aromas and using them to learn more about how we used to live.
Les mer »
Scientists Uncover a Gut-Brain Connection for Social DevelopmentTo learn to socialize, zebrafish need to trust their gut. Gut microbes encourage specialized cells to prune back extra connections in brain circuits that control social behavior, new University of Oregon research in zebrafish shows. The pruning is essential for the development of normal social be
Les mer »
How to Heal Your Gut — and Signs Your Gut Health Is LackingThe key to how to 'heal your gut,' is to practice everyday healthy habits, assuming you don't have a condition that requires medical attention. Here, gastroenterologists answer the question, 'How can I heal my gut,' detailing what foods heal your gut as well as lifestyle tips.
Les mer »