Science, Space and Technology News 2023
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In a C. elegans worm, the neuron HSN has a critical role in directing several coordinated behaviors. This image labels HSN in green, showing its extension all the way to the worm’s head . Credit: Flavell Lab/Picower Instituteis the only animal where the full connectome among neurons is known), and it had also been associated with egg-laying.
HSN is known to release a wide variety of neurotransmitter chemicals including serotonin, acetylcholine, and numerous peptides. Its release of serotonin and a neuropeptide called NLP-3 is known to drive egg-laying. To determine how the neuron drives speedy locomotion, the team systematically knocked out each HSN neurotransmitter and then stimulated HSN to see whether the worms could still speed up when HSN couldn’t produce one chemical or the other.
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