Dermatologists Call This Ingredient “A Needle-Free Alternative to Botox”—These 9 Products Fit the Bill

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Dermatologists Call This Ingredient “A Needle-Free Alternative to Botox”—These 9 Products Fit the Bill
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Clinically proven to improve the look of fine lines, this offering from Dr. Dennis Gross is a plumping, firming masterpiece.

With the Well+Good SHOP, our editors put their years of know-how to work in order to pick products they’re betting you’ll love. While our editors independently select these products, making a purchase through our links may earn Well+Good a commission. Happy shopping!There are plenty of serums and moisturizers on the market that promise to diminish the appearance of fine lines and wrinkles.

And how does it do that?"Argireline works on the neuromuscular junction just like Botox does, but with a different form of action and revealing a different result," says"a safe, needle-free alternative to Botox," the ingredient works by"inhibiting the release of neurotransmitters in the neuromuscular junction, producing a botox-like effect."

While Botox can completely erase wrinkles and lasts for months, argireline needs to be used more regularly to see comparable effects. According to, a twice-daily application of the ingredient reduced wrinkles by up to 48 percent over four weeks."Compared to Botox, argireline's effects are much more subtle," says Dr. Marcus."In addition, Argireline yields a very temporary effect, whereas the effects of Botox can be expected to last around three months.

If you're looking for a Botox-like effect that doesn't require a trip to the dermatologist's office, argireline is the ingredient to try. It contains argireline, four weights of hyaluronic acid, four different peptides, niacinamide and ectoin to rejuvenate the skin and act like filler, in that it visibly fills lines and gives the skin a plumper, fresher, bouncier look. We’re sold.

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