Two new studies find that adding immunotherapy to standard chemotherapy lengthens the time before tumors return.
to the standard chemotherapy regimen of carboplatin and paclitaxel reduced the risk that patients' advanced or recurrent endometrial cancer would return by up to 70%, depending on the types of tumors they had.study author Dr. Carol Aghajanian, a medical oncologist specializing in gynecologic cancers at Memorial Sloan Kettering Cancer Center in New York City.who received the combination treatment went, on average, more than a year before their disease progressed, compared to 8.
While women in the chemo-only group went, on average, 7.6 months before their cancer progressed, women with the mismatch repair-deficient tumor type that got chemotherapy plus immunotherapy are doing so well a year later, Dr. Pamela Soliman, a gynecologic oncologist at MD Anderson Cancer Center in Houston who was not involved in the new studies, said the findings were exciting.
Currently, immunotherapy is only approved for endometrial cancer as a second line of treatment, after chemotherapy. These findings suggest a significant advantage to using immunotherapy as part of the first line of treatment in these advanced cancers.
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