The detection of mobile genetic elements is crucial for exploring the ecology and evolution of microbial communities, and it has diverse implications in biotechnology and public health. geNomad is a computational framework that enables researchers to precisely identifiy and annotate plasmids and viruses in sequencing data on a large scale.
Durrant, M. G. et al. Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome.This paper identifies over a hundred thousand virus genomes in metagenomic sequencing data, expanding the number of known viral genes at that time by 16-fold.
Camargo, A. P. et al. IMG/VR v4: an expanded database of uncultivated virus genomes within a framework of extensive functional, taxonomic, and ecological metadata.This paper describes the IMG/VR v4 database, which was created using geNomad and includes more than 15 million sequences of viral genomes.
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