Influenza vaccination is associated with a reduced risk of stroke among adults, even if they aren't at high risk for stroke, according to new research. MedTwitter
Among the 4.1 million adults included in the researchers' analysis, about 1.8 million received at least one vaccination during the study period. Nearly 97,000 people received a flu vaccine in each year they were in the study, including 29,288 who received a shot in all 10 flu seasons included in the study.
The crude incidence of stroke was higher among people who had ever received an influenza vaccination, at 1.25%, compared with 0.52% among those who hadn't been vaccinated. However, after adjusting for age, sex, underlying conditions, and socioeconomic status, recent flu vaccination was associated with a 23% reduced risk of stroke.
Vaccination was associated with a larger reduction in stroke risk in men than in women, perhaps because unvaccinated men had a significantly higher baseline risk for stroke than unvaccinated women, the study authors write.In addition, vaccination was associated with a greater relative reduction in stroke risk in younger age groups, lower income groups, and those with diabetes, chronic obstructive pulmonary disease, and anticoagulant use.
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