A recent study links the FRYL gene to a new neurodevelopmental disorder in humans. They used fruit flies to establish that the loss of a functional copy of the FRY-like transcription coactivator (FRYL) gene is the underlying cause of this new disorder in fourteen individuals.
A recent study links the FRYL gene to a new neurodevelopmental disorder in humans. They used fruit flies to establish that the loss of a functional copy of the FRY-like transcription coactivator gene is the underlying cause of this new disorder in fourteen individuals.
Next, they found that the loss of both copies of this gene was lethal at the embryonic or larval stage, which gave a clue that it plays a critical role during development. Dr. Pan and others then created mutant clones lackingcauses developmental defects such as multiple wing hairs in the mutant wing clones as well as small, rough eyes caused by cell death in the mutant eye clones.
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