A small, proof-of-concept study in monkeys reveals the potential of a one-off gene therapy to treat people with alcohol use disorder who haven't responded to other treatments.
A new gene therapy that"resets" the brain's reward system could help treat alcohol use disorder, a new study in monkeys suggests.
Alcohol boosts the brain's production of dopamine, which leads to feelings of relaxation and improved mood. However, in AUD, the brain adapts by producing less dopamine on its own, meaning people need to drink more to achieve the same positive effects. Using a similar approach to what has already been used to treat Parkinson's disease and a rare genetic disorder known as aromatic L-amino acid decarboxylase deficiency, the harmless virus carried a gene that encodes the protein glial cell line-derived neurotrophic factor , which helps preserve and regrow neurons. By putting the GDNF gene into cells that make dopamine, the team assumed it would spur them to produce normal levels of the chemical.
Norge Siste Nytt, Norge Overskrifter
Similar News:Du kan også lese nyheter som ligner på denne som vi har samlet inn fra andre nyhetskilder.
Gene mutation may explain why some don't get sick from COVID-19 -- ScienceDailyPeople who contract COVID-19 but never develop symptoms -- the so-called super dodgers -- may have a genetic ace up their sleeve. They're more than twice as likely as those who become symptomatic to carry a specific gene variation that helps them obliterate the virus, according to a new study.
Les mer »
Gene Simmons' Dominatrix #3 FOC Preview: One Time in BangkokGet ready for a wild ride! GeneSimmonsDominatrix 3 brings fetish fantasy to the fore amid Bangkok's dangerous underbelly. Witness the chaotic action as Dom unsheathes new alliances, conspiracies, and war! comicpreview NewComicBookDay BleedingCool
Les mer »
Former Purdue men’s basketball coach Gene Keady inducted into Naismith Basketball Hall of FameKeady was the Purdue University men’s basketball coach for 25 years from 1980 through 2005. He accumulated 512 career NCAA wins and won six Big Ten titles.
Les mer »
Scientists Successfully Reverse Hearing Loss in MiceBy activating a defective gene in mice, the researchers were able to restore their hearing to almost normal levels.
Les mer »
The Deal With Drinking Alcohol While PregnantIs drinking alcohol while pregnant safe for baby? Read TheBump.com guide on alcohol during pregnancy to find out all you need to know.
Les mer »
Seven Spider Monkeys to be Repatriated to Mexico After Rescue at BorderBorder Patrol officials report that a group of seven spider monkeys will be returned to Mexico after they were rescued from smugglers in South Texas.
Les mer »