With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. Evolutionary geneticist Asher Cutter proposes that we call this evolutionary meddling “genetic welding.” In an opinion paper p
, he argues that we must scientifically and ethically scrutinize the potential consequences of genetic welding before we put it into practice.
In classical Mendelian genetics, we think about genes having a 50:50 chance of getting passed from parent to offspring, but this isn’t always the case. In a natural phenomenon known as “genetic drive,” some genes are able to bias their own transmission so that they are much more likely to be inherited.Genetic welding is the human-mediated version of this: introducing genes that have an unfair advantage when it comes to heritability into natural populations.
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What should we call evolution driven by genetic engineering? Genetic welding, says researcherWith CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations. Evolutionary geneticist Asher Cutter proposes that we call this evolutionary meddling 'genetic welding.' In an opinion paper published March 28 in the journal Trends in Genetics, he argues that we must scientifically and ethically scrutinize the potential consequences of genetic welding before we put it into practice.
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