Groundbreaking blood test could hold key to diagnosing Alzheimer's

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Groundbreaking blood test could hold key to diagnosing Alzheimer's
LifestyleAlzheimer’S DiseaseMental Illness
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Today's Video Headlines: 07/27/2024

It’s tricky to tell if memory problems are caused by Alzheimer’s. That requires confirming one of the — buildup of a sticky protein called beta-amyloid — with a hard-to-get brain scan or uncomfortable spinal tap. Many patients instead are diagnosed based on symptoms and cognitive exams.

“I have patients not infrequently who I am convinced have Alzheimer’s disease and I do testing and it’s negative,” Schindler said.Blood tests so far have been used mostly in carefully controlled research settings. But a new study of about 1,200 patients in Sweden shows they also can work in the real-world bustle of doctors’ offices — especially primary care doctors who see far more people with memory problems than specialists but have fewer tools to evaluate them.

Doctors and researchers should only use blood tests proven to have a greater than 90% accuracy rate, said Alzheimer’s Association chief science officer Maria Carrillo. Several companies are developing p-tau217 tests including ALZpath Inc., Roche, Eli Lilly and C2N Diagnostics, which supplied the version used in the Swedish study.Only doctors can order them from labs. The Alzheimer’s Association is working on guidelines and several companies plan to seek FDA approval, which would clarify proper use.

The tests aren’t yet for people who don’t have symptoms but worry about Alzheimer’s in the family — unless it’s part of enrollment in research studies, Schindler stressed. Inside the cartel coup that saw El Chapo's son lure rival drug kingpin 'El Mayo' to the US to be arrestedWayfair's biggest sale of the summer is here — shop our fave patio picks from Black Friday in JulyWayfair's Black Friday in July offers up to 80% off kitchen essentials — Shop KitchenAid, NutriBullet, more

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