Science, Space and Technology News 2024
A research collaboration of bioengineers and neurosurgeons has developed a new solution to re-sealing the dura that, using a multi-functional biomaterial, addresses key limitations of current repair methods. Credit: Peter Allen, Ryan Allen, and James C. Weaver. SEAS/MIT/Wyss
The dura also is a critical biological barrier that contains cerebrospinal fluid surrounding all CNS tissues. Consequently, spontaneous injury, trauma, or necessary surgical procedures may cause CSF to leak, which can threaten patients’ lives, neurological functions, and recovery. A new solution to re-sealing the dura has now been developed by a collaborative team of bioengineers at the Wyss Institute for Biologically Inspired Engineering at Harvard University and the Harvard John A.
The team showed that DTAs could deliver these same benefits when tested using human cadaveric tissue. “In light of the persistent trend toward minimally invasive neurosurgeries for patients’ benefit, an ideal dural sealant must not only be a better alternative to suture repair, but also be easier to handle and deploy in tight spaces – current repair methods are not good at both,” said Wu.
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