How a scientist-artist transformed our view of the brain

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How a scientist-artist transformed our view of the brain
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With the same unflinching scrutiny that Santiago Ramón y Cajal applied to cells, biographer Benjamin Ehrlich examines Cajal’s life.

Cajal’s observations ultimately gained traction with other scientists and earned him the 1906 Nobel Prize in physiology or medicine. He shared the prize with Camillo Golgi, the Italian physician who developed a stain that marked cells, called the black reaction. Golgi was a staunch proponent of the reticular theory, putting him at odds with Cajal, who used the black reaction to show discrete cells’ endings. The two men had not met before their trip to Stockholm to attend the awards ceremony.

Through his detailed drawings, Santiago Ramón y Cajal revealed a new view of the brain and its cells, such as these two Purkinje cells that Cajal observed in a pigeon’s cerebellum.Cajal and Golgi’s irreconcilable ideas — and their hostility toward each other — came through clearly from speeches they gave after their prizes were awarded. “Whoever believed in the ‘so-called’ independence of nerve cells, [Golgi] sneered, had not observed the evidence closely enough,” Ehrlich writes.

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