The Tasmanian tiger, a dog-sized striped carnivorous marsupial also called the thylacine, once roamed the Australian continent and adjacent islands, an apex predator that hunted kangaroos and other prey. Because of humans, the species is now extinct.
. But this study marked the first time that RNA - much less stable than DNA - has been recovered from an extinct species.
"RNA sequencing gives you a taste of the real biology and metabolism regulation that was happening in the cells and tissues of the Tasmanian tigers before they went extinct," said geneticist and bioinformatician Emilio Mármol Sánchez of the Centre for Palaeogenetics and SciLifeLab in Sweden, lead author of the study published in the journal"If we want to understand extinct species, we need to understand what gene complements they have and also what the genes were doing...
"Most researchers have thought that RNA would only survive for a very short time - like days or weeks - at room temperature. This is likely true when samples are wet or moist, but apparently not the case when they are dried," said evolutionary geneticist Love Dalén of the Centre for Palaeogenetics.
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