Identification of myelin as a protective factor implicates it as a possible therapeutic target for Alzheimer's. So concludes a preprint study that has not yet been peer-reviewed.
Autopsy studies have suggested that tau protein accumulation favors brain regions with less myelin.
Identification of myelin as a protective factor would implicate it as a possible therapeutic target for AD.The 612-member study population comprised select, biomarker-characterized patients from the Alzheimer's Disease Neuroimaging Initiative and the BioFINDER-1 study. Linear regression analysis, testing the association of functional connectivity, fiber tract myelination, and covariance of tau-PET scores between linked brain regions, demonstrated a significant association , with more myelinated tracts showing a lesser association with tau covariance.
An imaging template derived from healthy persons protected the MRI analysis from pathologic alterations in iron that could otherwise obfuscate the data. Understanding of the mechanism of protection would support the development of myelin-targeted therapies.The study was funded by the German Center for Neurodegenerative Diseases and by a grant from the Deutsche Forschungsgemeinschaft.
Norge Siste Nytt, Norge Overskrifter
Similar News:Du kan også lese nyheter som ligner på denne som vi har samlet inn fra andre nyhetskilder.
Characterizing Human Beings on a Molecular Level: People With Similar Faces Likely Have Similar DNAA collection of photos of genetically unrelated lookalikes, along with DNA analysis, has revealed that strong facial similarity is linked with shared genetic variants. The work will be published today (August 23rd) in the journal Cell Reports. “Our study provides a rare insight into human likenes
Les mer »
Alert level raised following Semisopochnoi explosionA historic eruption of Semisopochnoi was reported in 1873, with at least four others that may have occurred in the previous hundred years.
Les mer »
Leather Dresses That Will Take Your Look to the Next Level 2022 / 2023 » Fashion AllureLeather Dresses That Will Take Your Look to the Next Level bbloggers fbloggers fashionblogger fashionaddict fashiondiaries fashionista styleinspo fashionblog inspo
Les mer »
US new home sales plunge for sixth straight month to lowest level since 2016Purchases of new homes in the U.S. fell even more than expected in July as record-high home prices and rising borrowing costs priced buyers out of the market.
Les mer »
The Best Laser Printers To Bring Your Printing To The Next LevelIf you value speed and ultra-crisp print quality, consider getting a laser printer. We round up the best laser printers for home office and small businesses.
Les mer »
Trump’s condemnations of the FBI reach a startling new levelAs Donald Trump accuses federal law enforcement of committing “atrocities” and “destroying” the U.S., there's no modern precedent for rhetoric like this.
Les mer »