Salivary glands make unexpected use of tiny ionocytes, essential to frogs and fish
Looking deep within mammalian spit-producing glands, scientists were recently surprised to find an ancient cell type long thought to exist primarily in the slimy skin of frogs and fish. Such discoveries are rare in modern science—and researchers say these tiny cells could fill many more roles than previously thought.
Historically, Makarenkova says, “people didn't really pay much attention to the ionocyte.” The cells were well documented in frog and fish skins, where they help to maintain a healthy salt balance in aquatic environments. In 2018 researchers learned that a version exists in humans, too: Harvard University scientists unexpectedly found ionocytes in human lungs' lining.
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