Humans have used honey for its antimicrobial properties for millennia, and science has only recently been catching up.
MGO, which isn't present in other honeys, has been associated with antimicrobial properties.
So Nolan and colleagues tested different concentrations of this honey against the bacteria in tissue cultures. Taken from 16 patients infected with cystic fibrosis or bronchiectasis, the strains ofWhile all mānuka-related treatments were able to destroy, the whole honey proved more effective than isolated MGO, suggesting other active components in the honey may help overcome the bacteria's drug resistance mechanisms.
They found the aid of the honey drastically lowered the amount of amikacin needed for successful treatment from 16 micrograms per milliliter to just 2 micrograms per milliliter. This would significantly reduce the horrible side effects of the drug. "By combining a totally natural ingredient such as mānuka honey with amikacin, one of the most important yet toxic drugs used for treating Mycobacterium abscessus, we have found a way to potentially kill off these bacteria with eight times less drug than before,""This has the potential to significantly reduce amikacin-associated hearing loss and greatly improve the quality of life of so many patients – particularly those with cystic fibrosis.
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