It 'works like a charm.'
The human genes in question express a metabolic pathway that involves breaking down sugars to produce energy, the same mechanism that's a part of many common disorders .
"It seems weird since yeast lives as single cells and humans consist of a substantially more complex system, but the cells operate in a very similar way," said Pascale Daran-Lapujade, TU Delft researcher, and lead author of a new study published in the journal Cell Reports, in"As compared to human cells or tissues, yeast is a fantastic organism for its simplicity to grow and its genetic accessibility: its DNA can be easily modified to address fundamental questions," she...
"You might think that you cannot exchange the yeast version with the human one, because it’s such a specific and tightly regulated process both in human and yeast cells," she added. "But it works like a charm!"
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