A 53-year-old man in Germany has been declared cured of HIV.
The man was treated in 2013 for acute myeloid leukemia using donor stem cells known to have an HIV-resistant mutation. Now 53 years old, he said he plans to get involved in fundraising for research.
Since the bone marrow transplant procedure, researchers found immune cells in the patient’s body that reacted to HIV, as well as signs that the virus was no longer replicating. When the scientists transplanted the patient’s cells into mice, the virus failed to replicate. As a final test to see if he was cured, the patient stopped taking the HIV treatment known as ART , which suppresses HIV replication, in 2018.
“It shows it’s not impossible – it’s just very difficult – to remove HIV from the body,” Björn-Erik Jensen, MD, one of the patient’s doctors, told the journalThe patient is at least the third person to be declared cured of HIV,reported. Declaring someone cured happens once it is determined that the virus is no longer replicating or being stored in the body.
, which is a cancer that affects the parts of the body that make blood, such as bone marrow. That’s because of the high risks with the procedure,reported. But researchers are looking at whether HIV patients’ own bone marrow can be genetically changed to have the same mutation that was present in the Dusseldorf patient’s transplant.
More than 38 million people worldwide are living with HIV, which is a virus that attacks the body’s immune system by destroying white blood cells, thereby increasing the risk for other infections. Recently, promising vaccine trials for HIV were canceled because the experimental treatments were not effective.
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