Moderna's messenger RNA vaccine is being studied in combination with Merck's Keytruda to treat patients with high-risk melanoma, the deadliest form of skin cancer, in a phase two trial.
Moderna's vaccine is designed to trigger the immune system to deploy killer T cells that target the specific mutations of a patient's tumors. Merck's Keytruda is a monoclonal antibody, administered as an injection, that prevents certain cell proteins from stopping T cells from going on the attack.
The companies originally entered the agreement in 2016, but Merck is now exercising its option through a $250 million payment to Moderna. Merck will collaborate on the development and commercialization of the product. The companies will share all costs and profits equally.after developing one of the most successful vaccines against Covid-19 in collaboration with the U.S. National Institutes of Health.
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