Narcolepsy is associated with an increased risk for CVD, independent of common comorbid conditions and medications used to treat the disorder, new research showed.
HOUSTON — Narcolepsy is associated with a significantly increased risk for cardiovascular disease and major adverse cardiac events , independent of common comorbid conditions and medications commonly used to treat the chronic sleep disorder , according to two new studies.
This raises doubt as to whether narcolepsy itself directly leads to CVD or if it is the result of these comorbid health conditions. Additionally, some medications used to treat narcolepsy carry their own cardiovascular risks. They also had an increased risk for stroke , heart failure or myocardial infarction , and atrial fibrillation .
"Our study found that even after considering the presence of health conditions like obstructive sleep apnea, diabetes, hypertension, hyperlipidemia, and even depression, as well as medication use, there still appears to be an independent relationship between narcolepsy and CVD," the investigators said.
"However, it remains uncertain whether this is the primary mechanism related to CVD," they commented., Shaheen Lakhan, MD, a neurologist and researcher based in Miami, Florida, called for narcolepsy to be recognized as a significant contributor to higher CVD risk.
Abnormal Sleep Pattern Sleep Disorder Somnipathy Narcolepsy CV Risk Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Hypertension Cardiometabolic Risk Cardiometabolic Risk Factors Heart Failure Sleep Obstructive Sleep Apnea Obstructive Sleep Apnea Syndrome Obstructive Sleep Apnoea Obstructive Sleep Apnoea Syndrome
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