The drug candidate, called fabimycin, was shown to be potent against over 300 drug-resistant clinical isolates. Because the bacteria that cause urinary tract infections are becoming more and more resistant to many antibiotics, they are becoming more and more difficult to treat. Researchers report t
It has become increasingly difficult to treat infections as the bacteria that cause them are becoming resistant to antibiotics.
Because the bacteria that cause urinary tract infections are becoming more and more resistant to many antibiotics, they are becoming more and more difficult to treat. Researchers report the discovery of a new molecule that suppresses drug-resistant bacteria in lab experiments as well as in mice with pneumonia and urinary tract infections in a study published in. According to the researchers, the compound fabimycin may one day be used to treat severe bacterial infections in humans.
The microbes may also mutate to evade multiple drugs. Furthermore, treatments that do work aren’t very specific, leading them to also eradicate beneficial bacteria. Therefore, Paul Hergenrother and colleagues wanted to design a drug that could infiltrate the defenses of gram-negative bacteria and treat infections, while leaving other helpful microbes intact.
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