Our bodies connect us to the world. When people lose parts of their bodies to disease or traumatic injury, they often feel that they've lost a part of who they are, even experiencing a grief akin to losing a loved one.
We hypothesized that developing a similar environment could override scar formation at the time of injury and allow the body to reactivate dormant regenerative signals.as a way to create an isolated chamber for regeneration by blocking other signals that would direct the body to develop scars or undergo other processes. We then loaded the device with a cocktail of five drugs involved in normal animal development and tissue growth.
The limbs also responded to light pressure, meaning that they had a restored sense of touch, and allowed the frog to return to normal swimming behavior. And frogs that weren't treated with the device or the drug cocktail did not regrow their limbs, leaving stumps that were insensitive to touch and functionally impaired.
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