The scientists were cited for their work on click chemistry and bioorthogonal reactions, which are used to make cancer drugs, map DNA and create materials that are tailored to a specific purpose. — The Associated Press
STOCKHOLM — Three scientists were jointly awarded this year’s Nobel Prize in chemistry on Wednesday for developing a way of “snapping molecules together” that can be used to design better medicines, including ones that target diseases such as cancer more precisely.
“The problem was to find good chemical buckles,” he said. “They have to react with each other easily and specifically.” “Doing chemistry inside human patients to make sure that drugs go to the right place and stay away from the wrong place,” Bertozzi explained. Bertozzi, whose research is supported by the Howard Hughes Medical Institute, which also supports The Associated Press’ Health and Science Department, said she was grateful for the energy and enthusiasm that a Nobel Prize win will inject into the field.
“That makes it possible to attach molecules in very specific pre-defined ways,” he said, and gives scientists a very precise tool to build complex new molecules that can be used for drugs, synthetic materials and other uses. For example, that has allowed scientists to attach dyes to cancer cells to track their movements and analyze how they differ from healthy tissue.
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