Patrick Mahomes threw for 423 yards and three touchdowns to rally the Chiefs back from another double-digit deficit as Christian McCaffrey debuted for the 49ers.
SANTA CLARA, Calif. — Patrick Mahomes threw for 423 yards and three touchdowns to rally Kansas City back from another double-digit deficit in the Chiefs’ 44-23 victory over the San Francisco 49ers on Sunday.
Mecole Hardman scored on two TD runs and an 8-yard catch, Justin Watson caught a 4-yard TD and JuJu Smith-Schuster finished it off with a 45 yard catch and run. Clyde Edwards-Helaire also scored on a 16-yard run. The Niners dropped back-to-back games despite getting a boost from the addition this week of running back Christian McCaffrey, who had 62 yards on 10 scrimmage touches in his San Francisco debut.
The Chiefs took control with back-to-back touchdown drives to start the second half. They started the opening drive of the third quarter at the San Francisco 33 following a 48-yard kick return by Isiah Pacheco and a personal foul on Jauan Jennings. Edwards-Helaire scored three players later to make it 21-13.