Poop sleuths discover mysterious coronavirus in California’s sewage

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Poop sleuths discover mysterious coronavirus in California’s sewage
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Here’s what else is weird: Very similar “cryptic lineages” — viral fragments with novel patterns of mutations — have been found in the sewage of other cities, such as New York City and St. Louis, Missouri.

These findings were published in the journal Nature Communications on Thursday. Similar discoveries, not yet published, have reportedly been made in other U.S. cities.

One theory is that it’s incubating in someone with a weak immune system who is confined to a care facility. Perhaps this person has Long COVID and has been unable to fend off the infection — so the virus persists in their body for months, mutating as it multiplies. The new lineages appeared before omicron, but are similar to omicron, with 12 to 16 unusual mutations in the gene for the spike protein that studs the viral surface, and allows it to latch on to cells.

It was through wastewater surveillance, not testing, that scientists last December detected the arrival of omicron in the northern part of Santa Clara County. The variant has since gone on to sweep the nation. “Wastewater surveillance serves as an early warning system for the emergence of COVID-19 in a community,” said Kirby at a Friday morning media briefing. Many programs conduct genetic sequencing of the virus.

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