A fourth dose of the Pfizer/BioNTech Covid-19 vaccine seems to offer short-lived protection against infection overall, but protection against severe illness did not wane for at least several weeks, a new study says
The study, published Tuesday in the New England Journal of Medicine, looked at the health records of more than 1.25 million vaccinated people in Israel who were 60 or older from January through March 2022, a time when the Omicron coronavirus variant was the dominant strain.
For confirmed infection,"a fourth dose appears to provide only short-term protection and a modest absolute benefit," the researchers wrote. But when it comes to severe infection, the fourth shot seems to help."Overall, these analyses provide evidence for the effectiveness of a fourth vaccine dose against severe illness caused by Omicron variant as compared with a third dose administered more than four months later," the study says.
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