Lipid nanoparticles & mRNA show promise for treating hereditary blindness.
Scientists from the Oregon State University College of Pharmacy have shown in animal studies that it may be possible to treat a rare genetic condition that causes
Lipids are a diverse group of biomolecules that includes molecules like fatty acids and oils, as well as natural oils and waxes. Nanoparticles are extremely small pieces of material, with sizes ranging from one to one hundred billionths of a meter. Messenger RNA are genetic molecules that give cells the instructions they need to create a specific protein.
Studies on mice and non-human primates demonstrated that LNPs fitted with peptides were able to get past obstacles in the eye and reach the neural retina, where light is converted into electric signals that the brain then converts into images.
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New Treatment for Hereditary Blindness Possible Using Nanoparticles and mRNAScientists from the Oregon State University College of Pharmacy have demonstrated in animal models the possibility of using lipid nanoparticles and messenger RNA, the technology underpinning COVID-19 vaccines, to treat blindness associated with a rare genetic condition. Researchers developed nano
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