“Decreased mitochondrial membrane potential is an attractive explanation for the complex dysfunctions of aging.'
surrounds each mitochondrion. The interior layer has accordion-style pleats. Age-related declines in the voltage potential have been noted in earlier modeling studies by others.
Numerous essential functions of these cellular organelles, such as the synthesis of energy molecules, immunological signaling, and genetic regulation, are driven by the mitochondrial membrane potential. “Decreased mitochondrial membrane potential is an attractive explanation for the complex dysfunctions of aging. However, it is unclear if lessening of the mitochondria voltage potential is a cause or a consequence of cellular aging,” said researchers in their study, which was published inTo achieve the elusive goal of verifying causality, the researchers used optogenetics, a technology that uses light to precisely manipulate a biological process inside a cell.
“We were able to show that harnessing the energy of light to experimentally increase mitochondrial membrane during adulthood is alone sufficient to slow the rate ofAccording to the researchers, these findings tend to indicate that it may be possible to directly reverse the age-related reduction of a mitochondrial voltage potential to prevent the roundworms' physiologic decline.Mitochondrial dysfunction plays a central role in aging, but the exact biological causes are still being determined.
Norge Siste Nytt, Norge Overskrifter
Similar News:Du kan også lese nyheter som ligner på denne som vi har samlet inn fra andre nyhetskilder.
Methane intensity drops in Permian Basin despite increased production - Dallas Business JournalMethane intensity in the Permian Basin has decreased by more than 76% in the past 10 years, despite the increased production in the area.
Les mer »
China: Plug-In Car Sales Increased By 50% In November 2022The overall car sales in China decreased in November, but the plug-in electric car market does not stop growing, not even for a while.
Les mer »
Secrets to Aging Gracefully: Researchers Uncover Factors Linked to Optimal AgingFindings underline the importance of a strength-based rather than a deficit-based focus on aging and older adults. What are the keys to “successful” or optimal aging? A new study followed more than 7,000 middle-aged and older Canadians for approximately three years to identify the factors linked
Les mer »
Successful Aging: Here’s a novel approach to New Year’s resolutionsManagement consultant Peter Drucker proposes 5 resolutions for older adults that focus on embracing change and risk.
Les mer »
Meet the mercenary army boss ‘worse than Putin’ who could be Russia’s next leaderYevgeny Prigozhin is winning public support among extremists who believe their aging president is failing them.
Les mer »
Poor hydration linked to early aging and chronic disease, 25-year study findsFindings from the National Institutes of Health suggest that people who don't drink enough fluids could face a higher risk of disease, but some researchers aren't convinced.
Les mer »