Arrhythmogenic cardiomyopathy, a heart disease that particularly affects young athletes, can result in sudden death. The University of Basel has recently genetically modified mice that develop a disease comparable to that found in humans. The team was able to identify previously undiscovered mechani
Sudden cardiac arrest is a potentially fatal condition in which your heart suddenly stops beating.
Fans of the soccer team Sevilla FC will never forget the August 2007 game when 22-year-old Antonio Puerta went into cardiac arrest, collapsed on the field, and eventually passed away in the hospital. The athlete was later found to be suffering from a condition known as arrhythmogenic cardiomyopathy. Today, it is recognized that a number of gene mutations can trigger the condition. There is no treatment, even with an early diagnosis; only symptom management options are available.
To test this hypothesis, Spindler’s team introduced a mutation similar to that found in patients into the genome of mice. The cardiac function of these animals was then examined by Kuster’s group. The result: the genetically modified animals showed a heart disease with arrhythmia that resembled arrhythmogenic cardiomyopathy in humans. In addition, microscopic and biochemical analysis indeed showed reduced adhesion between the cardiac muscle cells.
Norge Siste Nytt, Norge Overskrifter
Similar News:Du kan også lese nyheter som ligner på denne som vi har samlet inn fra andre nyhetskilder.
Yes, You Need to Talk to Your Kids About Suicide — Here's Your Step-by-Step GuideWe asked experts to tell us exactly how we can have a conversation with our kids about this sensitive and heavy topic.
Les mer »
Giuliani One Step Closer to Being Disbarred in DC for Trying to Overturn Trump Loss'The only sanction that's appropriate' for trying to disenfranchise hundreds of thousands of voters 'is disbarment,' said the lawyer who argued the case for Giuliani's punishment.
Les mer »
Big Win for College Athletes as Labor Board Targets NCAA and Pac-12College football and basketball players are one step closer to being recognized as employees of their schools.
Les mer »
One of Pa.’s ‘most beautiful’ buildings is this one, finds studyA building in Pennsylvania has been crowned as one of the 'most beautiful' in the state.
Les mer »