Gut Microbes Influence Binge-Eating of Sweet Treats in Mice We have all been there. You just meant to have a single Oreo cookie as a snack, but then you find yourself going back for another, and another. Before you know it, you have finished off the entire package even though you were not all that
According to new California Institute of Technology research in mice, specific gut bacteria may suppress binge eating behavior.We have all been there. You just meant to have a single Oreo cookie as a snack, but then you find yourself going back for another, and another. Before you know it, you have finished off the entire package even though you were not all that hungry to begin with.
The new Caltech study demonstrates that the absence of certain gut bacteria causes mice to binge eat palatable foods. In fact, the findings show that mice with microbiotas disrupted by oral antibiotics consumed 50 percent more sugar pellets over two hours than mice with normal gut bacteria. When their microbiotas were restored through fecal transplants, the mice returned to normal feeding behavior.
“The gut microbiome has been shown to influence many behaviors and disease states in mouse models, from sociability and stress to Parkinson’s disease,” Mazmanian says. “The recent appreciation that feeding behaviors, driven by motivation, are subject to the composition of the gut microbiome has implications not just to obesity, diabetes, and other metabolic conditions but perhaps to overuse of alcohol, nicotine, or illicit substances that bring pleasure.
The gut microbiota contains hundreds of bacterial species, and the team suspected that some were more influential than others in driving the binge eating behavior.
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