With its tail flipping rhythmically from side to side, this strange synthetic fish scoots around in its salt and glucose solution, using the same power as our beating hearts.
– ended up decreasing swimming speeds and breaking the relationship between the mechanical stretching and triggering of the next contraction on the other side. This confirmed the ion channels were indeed involved with the rhythmic contractions.
Parker and colleagues also integrated a pacemaker-like system into the biohybrid: an isolated cluster of cells that control the frequency and coordination of these movements. "Because of the two internal pacing mechanisms, our fish can live longer, move faster, and swim more efficiently than previous work,"The tissue wide contractions of the biohybrid fish are comparable to the zebrafish that the biohybrid is modeled after – more efficiently propelling the little device around than mechanical robotic systems.
"Rather than using heart imaging as a blueprint, we are identifying the key biophysical principles that make the heart work, using them as design criteria, and replicating them in a system, a living, swimming fish, where it is much easier to see if we are successful,"
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