A lab-made protein protected mice from lethal doses of paralyzing toxins found in a variety of snakes, a new study reports.
Scientists have developed an antibody that shuts down paralyzing toxins in the venom of black mambas, king cobras and dozens of other sharp-toothed serpents. The antibody — a single protein manufactured in the lab — Science Translational Medicine
Scientists have tallied hundreds of venomous snake species across the globe. In North America, a person might stumble upon a western diamondback; in Africa, a puff adder; in South Asia, a saw-scaled viper. A bite from any one of these snakes can maim or kill. Venomous snakebites according to the World Health Organization. Lifesaving antivenoms exist, Jardine says, but they’re “built with 100-year-old technology.
His team’s approach could glide past those problems. In a collection of more than 60 billion lab-made antibodies, the team hunted for ones that target a particularly vicious venom component used by some snakes: long-chain three-finger alpha-neurotoxins.
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