This method could be helpful for elderly people.
The development of technologies to protect or enhance memory in older people is an enduring goal of translational medicine. Here we describe repetitive transcranial alternating current stimulation protocols for the selective, sustainable enhancement of auditory–verbal working memory and long-term memory in 65–88-year-old people.
Modulation of synchronous low-frequency, but not high-frequency, activity in parietal cortex preferentially improved working memory on day 3 and day 4 and 1 month after intervention, whereas modulation of synchronous high-frequency, but not low-frequency, activity in prefrontal cortex preferentially improved long-term memory on days 2–4 and 1 month after intervention. The rate of memory improvements over 4 days predicted the size of memory benefits 1 month later.
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