Silke Hauf and her research team made a surprisingly quiet discovery during their study on cell division. They observed that the expression of RNA in cells is always accompanied by a certain level of variability, or noise, in the amount of RNA produced. Interestingly, Hauf and her team identified mu
Fission yeast cells with single mRNA molecules of two ultra-low noise genes labeled with fluorophores . The cell nucleus, where RNA is synthesized, and the cell outlines are labeled in blue. Credit: Photo courtesy of Silke Hauf
“We have solid data for this phenomenon,” said Hauf, associate professor in the Department of Biological Sciences atOften upstaged by the more striking, well-publicized high-noise genes, Hauf and her team were intrigued by these ultra-low noise genes as they provide a window into the understanding of gene expression and gene expression noise.
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