Scientists use genomics to uncover syphilis transmission patterns in England, in a pioneering new approach for STI surveillance.
are highly conserved compared to other bacterial pathogens -- as they tend to transmit more frequently than they mutate -- subtle differences can still exist as it spreads through a population. By comparing how genetically relatedsamples are between individuals with a syphilis diagnosis, scientists hope to pinpoint the source of syphilis outbreaks and construct networks that capture its spread.
Dr Mathew Beale, first author of the study and senior staff scientist at the Wellcome Sanger Institute, said:"The COVID-19 pandemic has reimagined what scale is possible in genomic surveillance and this study capitalises on that, providing important background information on how fast the genomes ofevolve as syphilis spreads through a population.
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