Examining the interplay of environmental exposure with the airway microbiome provides insights for possible intervention in lung health
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Extended Data Fig. 1 Flowchart of sputum collection, quality control and microbiome analyses.
A total of 3,915 individuals were initially approached. 3,820 individuals completed the questionnaire. Of them, 3,737 individuals had body measurement , and 3,424 individuals further had acceptable spirometry measurement after quality control . 907 individuals with post-bronchodilator FEV1 below 35% predicted, unwilling or unable to participate, or unable to produce sputum after induction were excluded, leading to 2,517 sputum samples.
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