The case for including microbial sequences in the electronic health record - Nature Medicine

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The case for including microbial sequences in the electronic health record - Nature Medicine
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The case for including microbial sequences in the electronic health record. Comment from Vitali Sintchenko and EnricoCoiera, Sydney_Uni Macquarie_Uni

provide examples of the added value of genomic data in patient management and infection control. In the three examples, microbial genomic data offer high-resolution diagnostic information, enable the detection of genomic markers of drug-resistance in difficult-to-treat and high-consequence diseases and allow risk stratification for healthcare-associated infections.

However, advances in genomics and data analytics challenge this approach of withholding information to avoid confusion or misinterpretation by clinicians and encourage the full sharing of sequencing data as well as the provision of support for clinicians when interpreting data. Historically, clinicians have become adept at interpreting signal data such as electrocardiograms or radiological images, either as part of comprehensive training or for specific clinical issues.

While open databases can support open science and crowd-sourced discovery, genomic data linked to individual and public health records can support clinical trials and can be used to measure the outcomes of treatments and population health interventions.

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