The Massive Screwup That Could Let COVID Bypass Our Vaccines

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The Massive Screwup That Could Let COVID Bypass Our Vaccines
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Global attention is no longer focused on vaccine innovation, leaving open the nightmare scenario that fast mutating COVID will bypass our immunity.

After weeks at a two-year low, COVID casesin some countries. In the United States, there were 100,000 daily new infections, on average–up from 30,000 in mid-March.

There’s a lot of uncertainty here. “The virus may, or may not, evolve in the short term towards ever-greater vaccine-evasion,” Eric Bortz, a University of Alaska-Anchorage virologist and public health expert, told The Daily Beast. with strict lockdowns in recent months has only underscored the perils of major new COVID restrictions.The vaccines we’ve currently got are a mixed bag. They include old-fashioned Russian and Chinese jabs that use cold viruses as vectors for fragments of the coronavirus or contain whole killed SARS-CoV-2. There’s not a lot of good data on these vaccines, and many experts are skeptical of their effectiveness.

The inherent flexibility of mRNA vaccines makes that possible. The basic mRNA-vaccine formula is the same for any disease or variant of a disease. You just swap in new genetic material, depending on the thing you want to prevent. “We could use it to change the vaccine in a short time,” Ali Mokdad, a professor of health metrics sciences at the University of Washington Institute for Health, told The Daily Beast. “But it all depends on how fast the virus is mutating.

The nasal vaccines, administered by a spray, induce immunity in the mucus tissues of the nose and throat—where a COVID infection generally begins. Existing COVID vaccines are all injected into muscle tissue. The antibodies they produce, while effective against the virus, might be lessWhere a nasal vaccine is highly optimized for a respiratory virus like COVID, a pan-coronavirus takes the opposite tack. It aims to be universal rather than specific.

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