“Deconstruct to reconstruct.” FabricNano founder gaarons has set his sights on changing the production of petrochemical-derived and fermented materials—chief among them: plastic—by leveraging biological components. WIREDImpact Find out more:
If you are wondering what the future of manufacturing looks like, all you need to do is visit the fourth floor of a brick building in the London borough of Camden. There, in a Biosafety Level 2 laboratory obtained from refitting half of an open-plan office, chemists and biologists in goggles and white coats are busy operating bulky machinery and parsing the contents of reactors and vats filled with a thick yellow goo.
The process for creating products and materials by harnessing enzymes is well known: The ubiquitous high-fructose corn syrup that infests US foodstuffs is made by mixing cornstarch with a trio of proteins. “It looks like an assembly line: like, you’re just taking your input chemical, your feedstock. You’re putting it into the enzyme, handing it off to the next one, and making an ultimate product,” says FabricNano vice president for operations Eliza Eddison.
FabricNano’s idea was to bind proteins to strands of lab-made DNA, a material that had never been seriously experimented with in the industry. The team—which at the time still comprised cofounder Ferdinando Randisi, who had studied DNA theoretical biophysics at the University of Oxford—found that, indeed, when bound to a DNA scaffolding, the proteins did not get damaged, allowing them to keep working for much longer, making biomanufacturing cheaper.
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