In a finding that suggests sooner is better than later, a new trial shows that giving advanced treatment early to Crohn’s patients can dramatically improve their gut health.
In a finding that suggests sooner is better than later, a new trial shows that giving advanced treatment early to Crohn's patients can dramatically improve their gut health.shortly after their Crohn's diagnosis experienced an improvement in their symptoms and inflammatory markers related to the disease, researchers report.“We've shown that by treating earlier, we can achieve better outcomes for patients than have previously been reported,” said lead researcher Dr.
Patients were assigned at random to undergo one of two treatment strategies using infliximab, which works by blocking a protein found in the immune system. It is administered through IV drip or injection. The second group received “top-down” therapy, where they were given infliximab as soon as possible following diagnosis, regardless of the severity of their symptoms.test at the end of the trial. That sort of remission is very important, researchers said, because it's consistently associated with decreased risk of later complications in Crohn's disease.The top-down patients also had a tenfold lower need for urgent abdominal surgery within the first year of treatment, about 0.
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